DNA test for prostate cancer relapse
They compared genetic differences to the different outcomes the men experienced.
The researchers found that prostate cancer patients had high numbers of genetic mutations called ‘copy number variations’, in which sections of DNA are abnormally repeated or missing. Particular repeats and deletions were more common in patients who went onto have a rapid relapse, and the size of copy number variations tended to be larger in these patients as well. The researchers then used this information to create prediction models based on the DNA in different types of tissue samples.